Medicinal Chemistry Research Group
Research Centre for Natural Sciences, Budapest

Péter Ábrányi-Balogh

research fellow

Email: abranyi-balogh.peterttkhu
Phone: +36 1 3826 961

Scientific interests: chemical probes, covalent labelling of proteins, antibody-conjugates, new multicomponent reactions, beta-carboline and isoquinoline alkaloids, reaction mechanisms, organophosphorous compounds


Selected publications

  1. Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
    Douangamath, A.; Fearon, D.; Gehrtz, P.; Krojer, T.; Lukacik, P.; Owen, C. D.; Resnick, E.; Strain-Damerell, C.; Aimon, A.; Ábrányi-Balogh, P.; Brandaõ-Neto, J.; Carbery, A.; Davison, G.; Dias, A.; Downes, T. D.; Dunnett, L.; Fairhead, M.; Firth, J. D.; Jones, S. P.; Keeley, A.; Keserű, G. M.; Klein, H. F.; Martin, M. P.; Noble, M. E. M.; O’Brien, P.; Powell, A.; Reddi, R.; Skyner, R.; Snee, M.; Waring, M. J.; Wild, C.; London, N.; von Delft, F.; Walsh, M. A.
    bioRxiv, 2020, 2020.05.27.118117, accepted to Nature Communications

  2. Covalent fragment libraries in drug discovery
    Aaron Keeley, László Petri, Péter Ábrányi-Balogh, György M.Keserű
    Drug Discovery Today, 2020, 25 (6), 983-996.

  3. A road map for prioritizing warheads for cysteine targeting covalent inhibitors
    Péter Ábrányi-Balogh, László Petri, Tímea Imre, Péter Szijj, Andrea Scarpino, Martina Hrast, Ana Mitrović, Urša Pečar Fonovič, Krisztina Németh, Hélène Barreteau, David I. Roper, Kata Horváti, György G.Ferenczy, Janko Kos, Janez Ilaš, Stanislav Gobec, György M.Keserű
    European Journal of Medicinal Chemistry, 2018, 160, 94-107.

  4. Design and characterization of a heterocyclic electrophilic fragment library for the discovery of cysteine-targeted covalent inhibitors
    Aaron Keeley, Peter Abranyi-Balogh and George M Keserű
    MedChemComm, 2019, 10, 263-267.

  5. Synthesis and fluorescent properties of boroisoquinolines, a new family of fluorophores
    Dénes Sóvári, Attila Kormos, Orsolya Demeter, András Dancsó, György Miklós Keserű, Mátyás Milen and Péter Ábrányi-Balogh
    RSC Advances, 2018, 8, 38598-38605.